Vitrectomy for treatment of macular hole study group. Early vitrectomy for impending macular hole full text. Macular hole after diabetic vitrectomy the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Vitreous surgery for impending macular hole request pdf. Unclosed primary macular holes were defined as idiopathic macular holes that underwent vitrectomy surgery but were never observed to close in the postoperative period. Internal limiting membrane peeling versus no peeling for idiopathic. Inflammation and macular oedema after pars plana vitrectomy. Prospective randomized trial of vitrectomy or observation for stage 2. Vitrectomy for stage 1 macular holes identified by optical.
Results of a multicentered randomized clinical trial. Threeday facedown positioning for macular hole surgery. Results from a prospective randomized clinicaltrial. Repeat surgery in failed primary vitrectomy for macular. The purpose of this study is to assess the benefit of vitreous surgery in preventing fullthickness macular holes in patients with impending stage 1 macular holes. The treatment of idiopathic macular holes has been basically modeled, and vitreoretinal surgery is recognized as an effective treatment. The international vitreomacular traction study group. Idiopathic macular hole preferred practice pattern ophthalmology. Results of vitrectomy and the notouchtechnique using autologous. The vitrectomy for prevention of macular hole study group. Macular hole formation after pars plana vitrectomy for.
The international vitreomacular traction study group classification of vitreomacular adhesion, traction, and macular hole article pdf available. Gregor, moorfields macular hole study group report no. Vitrectomy surgery with the use of longacting gas and postoperative. Baseline characteristics, natural history, and risk factors to progression ineyes with stage 2 macular holes. Introduced about 15 years ago, surgery for macular hole including vitrectomy, fluidgas exchange and facedown postoperative positioning initially had an anatomic success rate of 58 percent. Pdf the international vitreomacular traction study group. Pdf outcomes of vitrectomy for longduration macular hole. Macular hole after diabetic vitrectomy full text view. Kim jw1, freeman wr, elhaig w, maguire am, arevalo jf, azen sp. In this group, 0% of eyes went on to develop a ftmh. The vitrectomy for macular hole study group vmhsg conducted an rct, including an observational arm. In a study conducted 15 years ago, the vitrectomy for prevention of macular hole study group was not able to prove the benefits and advantages of vitrectomy for treatment of impending macular.
It included 171 eyes with stage 2, 3 and 4 macular holes, and reported separately on the results of macular hole surgery in eyes with stage 2 holes kim et al. Kim jw1, freeman wr, azen sp, elhaig w, klein dj, bailey il. The vitrectomy for macular hole study group vmhsg conducted an rct,including an observational arm. In 1991, kelly and wendel described an effective surgical treatment for idiopathic macular holes. A comparative retrospective study between three groups of patients who underwent vitrectomy for longduration mh mean. Macular holes can be seen in highly myopic eyes or following ocular trauma, but the great majority are idiopathic. Sulfur hexafluoride sf 6 versus perfluoropropane c 3 f. Surgery called vitrectomy is the best way to treat a macular hole. The purpose of this study is to assess the benefit of vitreous.
Vitrectomy for the treatment of fullthickness stage 3 or 4 macular holes. Thestudy demonstrated only a modest benefit in the. A fullthickness macular hole developed in 10 37% of 27 patients in the vitrectomy group compared with 14 40% of 35 patients randomized to observation p 0. Vitrectomy has become the standard treatment for macular hole with anatomical success rates of 85100%. A macular hole is an anatomic opening in the retina that develops at the fovea. Baseline characteristics, natural history, and risk. The international vitreomacular traction study group classification of. Elhaig w, klein dj, bailey il, and the vitrectomy for macular hole study group. Listing a study does not mean it has been evaluated by the. A comparative study of vitrectomy combined with internal.
One of the initial major trials on ppv for stage 3 and 4 macular holes was the vitrectomy for treatment of macular hole study group. A multicentered clinical study of serum as adjuvant therapy for. Kim jw, freeman wr, azen sp, et al, vitrectomy for macular hole study group. Vitrectomy for prevention of macular hole study group. Vitrectomy for the treatment of fullthickness stage 3 or 4 macular. Ezra e, gregor zjmoorfields macular hole study group. Prospective randomized trial of vitrectomy or observation for stage 2 macular holes. Pars plana vitrectomy was introduced to treat fullthickness macular holes. This difference of 3% has a 95% confidence interval of 21%, 27%. Macular hole treatment american academy of ophthalmology. Macular hole has been believed to be a disorder of vitreomacular interface, which. This bubble helps flatten the macular hole and hold it in place while your eye heals. Freeman wr, azen sp, kim jw, elhaig w, mishell dr, 3rd, bailey i.
The study was terminated because of low recruitment. Macular hole reopening the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Visual acuity as a prognostic indicator in stage i macular. Twoyear results of a randomized clinical trial comparing natural history, vitrectomy, and. A multicentered clinical study of serum as adjuvant. The effect of postoperative facedown positioning and of longversus shortacting gas in macular hole surgery. Macular hole reopening full text view clinicaltrials. Your ophthalmologist removes the vitreous that is pulling on your macula. Outcomes of vitrectomy for longduration macular hole. Listing a study does not mean it has been evaluated by the u. However, the postoperative tamponade of gas will still make the patient uncomfortable and may have related complications. In the study, 50 patients with stage 2 or stage 3 idiopathic macular hole were positioned face down for 50 minutes of every hour for 3 days. Since then, the data from the vitrectomy for treatment of macular hole study group in 1997 established a clear benefit of surgical repair for patients with fullthickness holes, so the need to. The eye disease casecontrol study group reported a cohort of 198 patients with macular holes and normal fellow eyes examined at baseline, of whom.
358 164 281 1075 1272 1531 110 435 1562 773 629 1312 980 531 326 483 1370 206 234 619 689 340 945 1257 1039 918 945 179 1170 1278 970 1052 241 854 376 439